Possible neuroprotective trait of Dysophylla auricularia methanol extract

Muhammad Torequl Islam


This study evaluated the inhibitory capacity of hydroxyl radical (OH), nitric oxide radical (NO), lipid peroxidation and acetylcholinesterase (AChE) activity of methanol extract of Dysophylla auricularia (MDA) whole plant. For this MDA at 50-200 µg/mL was tested by taking trolox (TRO: 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) as a standard. The TRO was used at 50 µg/mL. The results suggest that, MDA concentration-dependently exhibited strong antioxidant and anti-AChE activities. Significant (p <0.05) activity was observed in the MDA and TRO co-treatment group. D. auricularia may be one of the good sources of neuroprotective phytoconstituents.


acetylcholinesterase; antioxidant; Dysophylla auricularia; neurological activity.

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